Congenital disabilities are called body structure changes that are evident from birth. As a result, they can alter the body's appearance, functionality, or both. The severity of a problem at birth may vary significantly. Any of the following situations increase the risk level: the presence of a genetic disease or flaw in the family tree. Use of drugs, alcohol, or tobacco products when carrying a child. Maternal age more than or equal to 35 years. Tests can help your doctor determine the likelihood that your unborn child will be affected by Down syndrome, neural tube abnormalities, or other uncommon genetic disorders.